We apply an integrative approach to capture protein/membrane assemblies in action, with the goal of understanding the molecular basis for cell morphology.
In vitro reconstitution
We use synthetic membrane systems to dissect molecular mechanism. We reconstitute protein assembly and activity in liposome and supported bilayer systems. Our goal is to recapture essential elements of membrane dynamics and structure from purified components.
credit image: pdb 6GCI, 6B8H, Fawcett The Cell